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Saturday, August 2, 2014



Will Strep-Throat kill your child?  What about your next Urinary Tract Infection?  Pneumonia?

Unfortunately, we are entering a time where the answer to that question is:  YES.   

Additionally, the US Government is more concerned with Opiate Prescription drug prescription rates and enforcement of those in legitimate pain management programs vs. worrying about what may in fact kill off the entire population!  The PRIORITIES of some in Government are so backwards, that the DEATH OF THE POPULATION is not a concern, but overuse of oxycodone is.  In the long-run, it doesn't matter if a few people abuse controlled substances if bacteria and parasites are going to kill our population in pandemic fashion.

CDC / WHO Scientists, Epidemiologist, Physicians etc, have been warning about the increasing resistance of bacteria to antibiotics.  Antibiotics, such a ceftriaxone, azithromycin, ciprofloxacin, flouroquinones, have all been used to treat fairly common conditions such as:

-Cellulitis:  Skin infections
-C.Difficilie:  Bacterial Diarrhea
-Tuberculosis: Lung Infection / Kidney Infection
- Salmonella:  Food poisoning
- Cystitis: Bladder Infection
- Streptococcal Infections:  "Strep Throat"
- Enterococcal Infections:  Stomach Bugs / "Stomach Flu"
- Conjunctivitis:  Eye Infections

Here is a full listing from the CDC (Adapted from the CDC 2013 Threat Report) and the pathogenic bacteria with their associated illnesses:
Acinetobacter is a type of gram-negative bacteria that is a cause of pneumonia or bloodstream infections among critically ill patients. Many of these bacteria have become very resistant to antibiotics.
Anthrax is a serious disease caused by Bacillus anthracis, a bacterium that forms spores. Anthrax most commonly occurs in wild and domestic mammalian species, but it can also occur in humans when they are exposed to infected animals or to tissue from infected animals or when anthrax spores are used as a bioterrorist weapon. Some strains of B. anthracis may be naturally resistant to certain antibiotics and not others. In addition, there may be biologically mutant strains that are engineered to be resistant to various antibiotics.
Campylobacter usually causes diarrhea (often bloody), fever, and abdominal cramps, and sometimes causes serious complications such as temporary paralysis.
Untreatable and hard-to-treat infections from carbapenem-resistant Enterobacteriaceae (CRE) bacteria are on the rise among patients in medical facilities. CRE have become resistant to all or nearly all the antibiotics we have today. Almost half of hospital patients who get bloodstream infections from CRE bacteria die from the infection.
Neisseria gonorrhoeae causes gonorrhea, a sexually transmitted disease that can result in discharge and inflammation at the urethra, cervix, pharynx, or rectum.
Group B Streptococcus (GBS) is a type of bacteria that can cause severe illnesses in people of all ages, ranging from bloodstream infections (sepsis) and pneumonia to meningitis and skin infections.
Methicillin-resistant Staphylococcus aureus (MRSA) causes a range of illnesses, from skin and wound infections to pneumonia and bloodstream infections that can cause sepsis and death. Staph bacteria, including MRSA, are one of the most common causes of healthcare-associated infections.
One of the leading causes of bacterial meningitis in children and young adults in the United States is the bacterium Neisseria meningitidis. Meningitis caused by this bacterium is known as meningococcal disease. During 2007-2008 the first reported cases of fluoroquinolone-resistant Neisseria meningitides were reported in the United States
Non-typhoidal Salmonella (serotypes other than Typhi, Paratyphi A, Paratyphi B, and Paratyphi C) usually causes diarrhea (sometimes bloody), fever, and abdominal cramps. Some infections spread to the blood and can have life-threatening complications.
Shigella usually causes diarrhea (sometimes bloody), fever, and abdominal pain. Sometimes it causes serious complications such as reactive arthritis. High-risk groups include young children, people with inadequate handwashing and hygiene habits, and men who have sex with men.
Streptococcus pneumoniae (S. pneumoniae, or pneumococcus) is the leading cause of bacterial pneumonia and meningitis in the United States. It also is a major cause of bloodstream infections and ear and sinus infections.
Tuberculosis (TB) is among the most common infectious diseases and a frequent cause of death worldwide. TB is caused by the bacteria Mycobacterium tuberculosis (M. tuberculosis) and is spread most commonly through the air. M. tuberculosis can affect any part of the body, but disease is found most often in the lungs. In most cases, TB is treatable and curable with the available first-line TB drugs; however, in some cases, M. tuberculosis can be resistant to one or more of the drugs used to treat it. Drug-resistant TB is more challenging to treat — it can be complex and requires more time and more expensive drugs that often have more side effects. Extensively Drug-Resistant TB (XDR TB) is resistant to most TB drugs; therefore, patients are left with treatment options that are much less effective. The major factors driving TB drug resistance are incomplete or wrong treatment, short drug supply, and lack of new drugs. In the United States most drug-resistant TB is found among persons born outside of the country.
Salmonella serotype Typhi causes typhoid fever, a potentially life-threatening disease. People with typhoid fever usually have a high fever, abdominal pain, and headache. Typhoid fever can lead to bowel perforation, shock, and death.
Enterococci cause a range of illnesses, mostly among patients receiving healthcare, but include bloodstream infections, surgical site infections, and urinary tract infections.
Staphylococcus aureus is a common type of bacteria that is found on the skin. During medical procedures when patients require catheters or ventilators or undergo surgical procedures, Staphylococcus aureus can enter the body and cause infections. When Staphylococcus aureus becomes resistant to vancomycin, there are few treatment options available because vancomycin-resistant S. aureus bacteria identified to date were also resistant to methicillin and other classes of antibiotics.

Antibiotics and similar drugs, together called antimicrobial agents, have been used for the last 70 years to treat patients who have infectious diseases. Since the 1940s, these drugs have greatly reduced illness and death from infectious diseases. Antibiotic use has been beneficial and, when prescribed and taken correctly, their value in patient care is enormous. However, these drugs have been used so widely and for so long that the infectious organisms the antibiotics are designed to kill have adapted to them, making the drugs less effective. Many fungi, viruses, and parasites have done the same. Some microorganisms may develop resistance to a single antimicrobial agent (or related class of agent), while others develop resistance to several antimicrobial agents or classes. These organisms are often referred to as multidrug-resistant or MDR strains. In some cases, the microorganisms have become so resistant that no available antibiotics are effective against them.

Drug Resistance Is Everywhere

Antimicrobial drug resistance occurs everywhere in the world and is not limited to industrialized nations. Hospitals and other healthcare settings are battling drug-resistant organisms that spread inside these institutions. Drug-resistant infections also spread in the community at large. Examples include drug-resistant pneumonias, sexually transmitted diseases (STDs), and skin and soft tissue infections.

The Effects of Antimicrobial Drug Resistance Are Far-Reaching

People infected with drug-resistant organisms are more likely to have longer and more expensive hospital stays, and may be more likely to die as a result of the infection. When the drug of choice for treating their infection doesn’t work, they require treatment with second- or third-choice drugs that may be less effective, more toxic, and more expensive. This means that patients with an antimicrobial-resistant infection may suffer more and pay more for treatment.

Trends in Drug Resistance

  • Reports of methicillin-resistant Staphylococcus aureus (MRSA)—a potentially dangerous type of staph bacteria that is resistant to certain antibiotics and may cause skin and other infections—in persons with no links to healthcare systems have been observed with increasing frequency in the United States and elsewhere around the globe.
  • The agricultural use of antibiotics in food-producing animals also contributes to the emergence, persistence, and spread of resistant bacteria. Resistant bacteria can be transmitted to humans through the foods we eat.
  • Multi-drug resistant Klebsiella species and Escherichia coli have been isolated in hospitals throughout the United States.
  • Antibiotic-resistant Streptococcus pneumoniae infections have significantly declined, but remain a concern in some populations.
  • Antimicrobial resistance is emerging among some fungi, particularly those fungi that cause infections in transplant patients with weakened immune systems.
  • Antimicrobial resistance has also been noted with some of the drugs used to treat human immunodeficiency virus (HIV) infections and influenza.
  • The development of antimicrobial resistance to the drugs used to treat malaria infections has been a continuing problem in many parts of the world for decades. Antimicrobial resistance has developed to a variety of other parasites that cause infection.
It’s been called public health’s ticking time bomb. Antibiotic resistance—when bacteria don’t respond to the drugs designed to kill them—threatens to return us to the time when simple infections were often fatal. Today, antibiotic resistance annually causes more than 2 million illnesses and 23,000 deaths in the United States. Tomorrow, if it continues on its current course, could be even worse:
  • A simple cut of the finger could lead to a life-threatening infection.
  • Common surgical procedures, such as hip and knee replacements, would be far riskier because of the danger of infection.
  • Dialysis patients could develop untreatable bloodstream infections.
  • Life-saving treatments that suppress immune systems, such as chemotherapy and organ transplants, could potentially cause more harm than good.
7Antibiotic Resistance Threats
  1. Clostridium difficile (C. difficile) causes deadly diarrhea mostly in people who’ve recently had medical care and antibiotics.
  2. Carbapenem-resistant Enterobacteriaceae (CRE) are nightmare bacteria that are resistant to nearly all antibiotics and spread easily. 
  3. MDR Neisseria gonorrhoeae causes gonorrhea and is showing resistance to antibiotics usually used to treat it. 
  4. Extended-spectrum β-lactamase-producing Enterobacteriaceae (ESBL) are bacteria one step away from becoming CRE.
  5. MDR Salmonella causes about 100,000 illnesses in the US each year; resistant infections are more severe.
  6. Methicillin-resistant Staphylococcus aureus (MRSA) causes skin and wound infections, pneumonia, and bloodstream infections. 
  7. MDR Pseudomonas causes healthcare-associated pneumonia and bloodstream infections; some strains are resistant to nearly all antibiotics.

The solution

We need to outsmart antibiotic resistance - now. CDC identified four core actions to be addressed by all partners in AR:
  • Detect and track patterns of antibiotic resistance.
  • Respond to outbreaks involving antibiotic-resistant bacteria.
  • Prevent infections from occurring and resistant bacteria from spreading.
  • Discover new antibiotics and new diagnostic tests for resistant bacteria.
  • (Source: CDC Drug Resistance )

Is it too late?  Some scientists seem to think so.  Others are more optimistic that different treatments other than antibiotics will eventually become more effective.  In any case, this is TRULY a race against time / Mother Nature!   Pathogens are always changing, and they are changing faster than medications can get researched and approved.  And, drug manufacturers are no longer interested in producing antibiotics... the profit level isn't there once Research and Development costs are added in.  Plus, other less-critical medications such as those that treat "erectile disfunction", "depression", and a host of other mood disorders is much more profitable and glamorous than the next antibiotic.  

In my personal opinion, all other drug research and trials should be banned until the next 10 levels of antibiotic therapies are produced!  We already have tried and true medications that are effective for:

-Cold/Flu Symptoms
-Jock Itch / Athlete's Foot
-Dry Eyes
-Diet Supplements
-Blood Pressure Medications
-Cardiac Rhythm Medications
-GastroIntestinal Disorders
-Muscle Spasms
-Sexual Disfunction
-Alzheimers Disease

THE TIME IS NOW, TO DEMAND ANTIBIOTIC RESEARCH AND DEVELOPMENT.... THERE IS NO NEED FOR ANY FURTHER CLASSIFICATION OF MEDICATIONS TO BE CREATED UNTIL WE SOLVE THIS PROBLEM!  (Many "new" medications are simply a blending of older, effective medications into one tablet instead of two or three separate tablets anyway).   Demand, scream, write letters, make videos, whatever it takes... to the FDA, CDC, Congress, to insist on focusing on this issue!  For if not... we won't need to focus on many other issues much longer.  It's that serious.

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